CD80(+) and CD86(+) B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis

BACKGROUND: Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Currently, there are no disease-modifying therapies with long-term clinical benefits or validated biomarke...

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Bibliographic Details
Main Authors: Menezes, Soraya Maria, Decanine, Daniele, Brassat, David, Khouri, Ricardo, Schnitman, Saul V, Kruschewsky, Ramon, López, Giovanni, Alvarez, Carolina, Talledo, Michael, Gotuzzo, Eduardo, Vandamme, Anne-Mieke, Galvão-Castro, Bernardo, Liblau, Roland, Weyenbergh, Johan Van
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922160/
https://ncbi.nlm.nih.gov/pubmed/24472094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-18
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