Leptospira Interrogans Induces Fibrosis in the Mouse Kidney through Inos-Dependent, TLR- and NLR-Independent Signaling Pathways

BACKGROUND: Leptospira (L.) interrogans are bacteria responsible for a worldwide reemerging zoonosis. Rodents carry L. interrogans asymptomatically in their kidneys and excrete bacteria in the urine, contaminating the environment. Humans get infected through skin contact and develop a mild or severe...

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Hauptverfasser: Fanton d'Andon, Martine, Quellard, Nathalie, Fernandez, Béatrice, Ratet, Gwenn, Lacroix-Lamandé, Sonia, Vandewalle, Alain, Boneca, Ivo G., Goujon, Jean-Michel, Werts, Catherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907306/
https://ncbi.nlm.nih.gov/pubmed/24498450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002664
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