APOBEC3B is an enzymatic source of mutation in breast cancer

Multiple mutations are required for cancer development, and genome sequencing has revealed that several cancers, including breast, have somatic mutation spectra dominated by C-to-T transitions(1–9). Most of these mutations occur at hydrolytically disfavored(10) non-methylated cytosines throughout th...

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Bibliografski detalji
Glavni autori: Burns, Michael B., Lackey, Lela, Carpenter, Michael A., Rathore, Anurag, Land, Allison M., Leonard, Brandon, Refsland, Eric W., Kotandeniya, Delshanee, Tretyakova, Natalia, Nikas, Jason B., Yee, Douglas, Temiz, Nuri A., Donohue, Duncan E., McDougle, Rebecca M., Brown, William L., Law, Emily K., Harris, Reuben S.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907282/
https://ncbi.nlm.nih.gov/pubmed/23389445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11881
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