APOBEC3B is an enzymatic source of mutation in breast cancer

Multiple mutations are required for cancer development, and genome sequencing has revealed that several cancers, including breast, have somatic mutation spectra dominated by C-to-T transitions(1–9). Most of these mutations occur at hydrolytically disfavored(10) non-methylated cytosines throughout th...

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מידע ביבליוגרפי
Main Authors: Burns, Michael B., Lackey, Lela, Carpenter, Michael A., Rathore, Anurag, Land, Allison M., Leonard, Brandon, Refsland, Eric W., Kotandeniya, Delshanee, Tretyakova, Natalia, Nikas, Jason B., Yee, Douglas, Temiz, Nuri A., Donohue, Duncan E., McDougle, Rebecca M., Brown, William L., Law, Emily K., Harris, Reuben S.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907282/
https://ncbi.nlm.nih.gov/pubmed/23389445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11881
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