Epigenetic Regulation of Nanog by MiR-302 Cluster-MBD2 Completes Induced Pluripotent Stem Cell Reprogramming

While most somatic cells undergoing induced pluripotent stem (iPS) cell reprogramming with Yamanaka factors accumulate at stable partially reprogrammed stages, the molecular mechanisms required to achieve full reprogramming are unknown. MicroRNAs (miRNAs) fine-tune mRNA translation and are implicate...

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Bibliographic Details
Main Authors: Lee, Man Ryul, Prasain, Nutan, Chae, Hee-Don, Kim, Young-June, Mantel, Charlie, Yoder, Mervin C., Broxmeyer, Hal E.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904370/
https://ncbi.nlm.nih.gov/pubmed/23255147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1302
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