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Mechanisms of Ghrelin Anti-Heart Failure: Inhibition of Ang II-Induced Cardiomyocyte Apoptosis by Down-Regulating AT1R Expression
BACKGROUND: Ghrelin is a novel growth hormone–releasing peptide administered to treat chronic heart failure (CHF). However, the underlying mechanism of its protective effects against heart failure (HF) remains unclear. METHODS AND RESULTS: A total of 68 patients with CHF and 20 healthy individuals w...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897516/ https://ncbi.nlm.nih.gov/pubmed/24465706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085785 |
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