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Advanced glycation end products induce fibrogenic activity in NASH by modulating the TNFα converting enzyme activity

Advanced glycation end products (AGEs) accumulate in patients with diabetes, yet the link between AGEs and the inflammatory and fibrogenic activity in non-alcoholic steatohepatitis (NASH) has not been explored. TNFα converting enzyme (TACE) is at the center of inflammatory processes. As the main nat...

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Detalhes bibliográficos
Main Authors: Joy, Jiang X, Chen, Xiangling, Fukada, Hiroo, Serizawa, Nobuko, Devaraj, Sridevi, Török, Natalie J
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897213/
https://ncbi.nlm.nih.gov/pubmed/23703665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26491
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