Genome wide association and linkage analyses identified three loci—4q25, 17q23.2, and 10q11.21—associated with variation in leukocyte telomere length: the Long Life Family Study

Leukocyte telomere length is believed to measure cellular aging in humans, and short leukocyte telomere length is associated with increased risks of late onset diseases, including cardiovascular disease, dementia, etc. Many studies have shown that leukocyte telomere length is a heritable trait, and...

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Autori principali: Lee, Joseph H., Cheng, Rong, Honig, Lawrence S., Feitosa, Mary, Kammerer, Candace M., Kang, Min S., Schupf, Nicole, Lin, Shiow J., Sanders, Jason L., Bae, Harold, Druley, Todd, Perls, Thomas, Christensen, Kaare, Province, Michael, Mayeux, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
Soggetti:
Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894567/
https://ncbi.nlm.nih.gov/pubmed/24478790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00310
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