CD56(neg)CD16(+) NK cells are activated mature NK cells with impaired effector function during HIV-1 infection

BACKGROUND: A subset of CD3(neg)CD56(neg)CD16(+) Natural Killer (NK) cells is highly expanded during chronic HIV-1 infection. The role of this subset in HIV-1 pathogenesis remains unclear. The lack of NK cell lineage-specific markers has complicated the study of minor NK cell subpopulations. RESULTS...

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Bibliographic Details
Main Authors:	Milush, Jeffrey M, López-Vergès, Sandra, York, Vanessa A, Deeks, Steven G, Martin, Jeffrey N, Hecht, Frederick M, Lanier, Lewis L, Nixon, Douglas F
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2013
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3892122/ https://ncbi.nlm.nih.gov/pubmed/24351015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-158
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CD56(neg)CD16(+) NK cells are activated mature NK cells with impaired effector function during HIV-1 infection

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