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Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 5/GPR49 Activates G(12/13)-Rho GTPase Pathway

Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5/GPR49) is highly expressed in adult stem cells of various tissues, such as intestine, hair follicles, and stomach. LGR5 is also overexpressed in some colon and ovarian tumors. Recent reports show that R-spondin (RSPO) family ligands b...

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Detaylı Bibliyografya
Asıl Yazarlar: Kwon, Mi So, Park, Bi-oh, Kim, Ho Min, Kim, Sunhong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Korea Society for Molecular and Cellular Biology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887977/
https://ncbi.nlm.nih.gov/pubmed/23912594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-0173-z
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