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Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 5/GPR49 Activates G(12/13)-Rho GTPase Pathway
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5/GPR49) is highly expressed in adult stem cells of various tissues, such as intestine, hair follicles, and stomach. LGR5 is also overexpressed in some colon and ovarian tumors. Recent reports show that R-spondin (RSPO) family ligands b...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Korea Society for Molecular and Cellular Biology
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887977/ https://ncbi.nlm.nih.gov/pubmed/23912594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-0173-z |
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