A Murine Model of Inflammatory Bladder Disease: Cathelicidin Peptide Induced Bladder Inflammation and Treatment With Sulfated Polysaccharides

PURPOSE: Studies show that LL-37 is a naturally occurring urinary defensin peptide that is up-regulated during urinary tract infections. Although normal urinary LL-37 levels are antimicrobial, we propose that increased LL-37 may trigger bladder inflammation. We further suggest that anti-inflammatory...

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Detalhes bibliográficos
Main Authors: Oottamasathien, Siam, Jia, Wanjian, McCoard, Lindsi, Slack, Sean, Zhang, Jianxing, Skardal, Aleksander, Job, Kathleen, Kennedy, Thomas P., Dull, Randal O., Prestwich, Glenn D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887035/
https://ncbi.nlm.nih.gov/pubmed/21855919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2011.03.099
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