Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes

Myocyte hypertrophy antecedent to heart failure involves changes in global gene expression, although the preceding mechanisms to coordinate DNA accessibility on a genomic scale are unknown. Chromatin-associated proteins alter chromatin structure by changing their association with DNA, thereby alteri...

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Main Authors: Monte, Emma, Mouillesseaux, Kevin, Chen, Haodong, Kimball, Todd, Ren, Shuxun, Wang, Yibin, Chen, Jau-Nian, Vondriska, Thomas M., Franklin, Sarah
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
Teme:
Muscle Mechanics and Ventricular Function
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882469/
https://ncbi.nlm.nih.gov/pubmed/24077883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00529.2013
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