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Essential role of axonal VGSC inactivation in time-dependent deceleration and unreliability of spike propagation at cerebellar Purkinje cells

BACKGROUND: The output of the neuronal digital spikes is fulfilled by axonal propagation and synaptic transmission to influence postsynaptic cells. Similar to synaptic transmission, spike propagation on the axon is not secure, especially in cerebellar Purkinje cells whose spiking rate is high. The c...

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Autors principals: Yang, Zhilai, Gu, Erwei, Lu, Xianfu, Wang, Jin-Hui
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880351/
https://ncbi.nlm.nih.gov/pubmed/24382121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-7-1
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