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Downregulation of Sulfotransferase Expression and Activity in Diseased Human Livers

Sulfotransferase (SULT) function has been well studied in healthy human subjects by quantifying mRNA and protein expression and determining enzyme activity with probe substrates. However, it is not well known if sulfotransferase activity changes in metabolic and liver disease, such as diabetes, stea...

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Détails bibliographiques
Auteurs principaux: Yalcin, Emine B., More, Vijay, Neira, Karissa L., Lu, Zhenqiang James, Cherrington, Nathan J., Slitt, Angela L., King, Roberta S.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876809/
https://ncbi.nlm.nih.gov/pubmed/23775849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.050930
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