CAWS administration increases the expression of interferon γ and complement factors that lead to severe vasculitis in DBA/2 mice

BACKGROUND: Candida albicans water-soluble fraction (CAWS), a mannoprotein-β-glucan complex obtained from the culture supernatant of C. albicans NBRC1385, causes CAWS-mediated vasculitis (CAWS-vasculitis) in B6 and DBA/2 mice with mild and lethal symptoms, respectively. Why CAWS is lethal only in DB...

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Bibliographic Details
Main Authors: Nagi-Miura, Noriko, Okuzaki, Daisuke, Torigata, Kosuke, Sakurai, Minami A, Ito, Akihiko, Ohno, Naohito, Nojima, Hiroshi
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876726/
https://ncbi.nlm.nih.gov/pubmed/24063402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-14-44
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