A mechanism of benefit of soy genistein in asthma: inhibition of eosinophil p38-dependent leukotriene synthesis

BACKGROUND: Dietary intake of the soy isoflavone genistein is associated with reduced severity of asthma, but the mechanisms responsible for this effect are unknown. OBJECTIVE: To determine whether genistein blocks eosinophil leukotriene C(4) (LTC(4)) synthesis and to evaluate the mechanism of this...

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Main Authors: Kalhan, R., Smith, L. J., Nlend, M. C., Nair, A., Hixon, J. L., Sporn, P. H. S.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873088/
https://ncbi.nlm.nih.gov/pubmed/17979994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2007.02862.x
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