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High-resolution melt analysis to detect sequence variations in highly homologous gene regions: application to CYP2B6

High-resolution melt (HRM) analysis using ‘release-on-demand’ dyes, such as EvaGreen(®) has the potential to resolve complex genotypes in situations where genotype interpretation is complicated by the presence of pseudogenes or allelic variants in close proximity to the locus of interest. We explore...

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Detaylı Bibliyografya
Asıl Yazarlar: Twist, Greyson P, Gaedigk, Roger, Leeder, J Steven, Gaedigk, Andrea
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866959/
https://ncbi.nlm.nih.gov/pubmed/23746185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.13.66
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