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BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling

The taxanes are effective microtubule-stabilizing chemotherapy drugs used in the treatment of various solid tumors. However, the emergence of drug resistance hampers their clinical efficacy. The molecular basis of clinical taxane resistance remains poorly understood. Breast cancer 1, early onset gen...

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Detalhes bibliográficos
Main Authors: Sung, M, Giannakakou, P
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865028/
https://ncbi.nlm.nih.gov/pubmed/23524581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.85
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