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Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension()
Nitric oxide (NO)-derived metabolites including the anion nitrite can recycle back to NO and thus complement NO formation independent of NO synthases. While nitrite is as a major vascular storage pool and source of NO, little is known about drugs that increase tissue nitrite concentrations. This stu...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Elsevier
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863772/ https://ncbi.nlm.nih.gov/pubmed/24363994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.11.004 |
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