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Plasma amino acids imbalance in cirrhotic patients disturbs the tricarboxylic acid cycle of dendritic cell

An imbalance of plasma amino acids (AA) is observed cirrhotic patients. Here we report that the imbalance suppresses the maturation of dendritic cells (DCs) by reducing the intracellular ATP due to interference with the mitochondrial tricarboxylic acid (TCA) cycle. We used serum-free culture medium...

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Detaylı Bibliyografya
Asıl Yazarlar: Kakazu, Eiji, Kondo, Yasuteru, Kogure, Takayuki, Ninomiya, Masashi, Kimura, Osamu, Ueno, Yoshiyuki, Shimosegawa, Tooru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857572/
https://ncbi.nlm.nih.gov/pubmed/24322372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03459
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