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Role of P-Glycoprotein Expression and Function in Cystinotic Renal Proximal Tubular Cells

P-glycoprotein (P-gp) is an ATP-dependent transporter localized at the apical membrane of the kidney proximal tubules, which plays a role in the efflux of cationic and amphipathic endogenous waste products and xenobiotics, such as drugs, into urine. Studies in mice deficient in P-gp showed generaliz...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Peeters, Karen, Wilmer, Martijn J., Schoeber, Joost P., Reijnders, Dorien, van den Heuvel, Lambertus P., Masereeuw, Rosalinde, Levtchenko, Elena
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857058/
https://ncbi.nlm.nih.gov/pubmed/24309308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics3040782
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