Complement factor H-derived short consensus repeat 18–20 enhanced complement-dependent cytotoxicity of ofatumumab on chronic lymphocytic leukemia cells

The antitumor activity of monoclonal antibodies in the treatment of chronic lymphocytic leukemia is mediated mainly by antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Unfortunately, the efficacy of complement-dependent cytotoxicity is strongly restricted due to the ex...

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Bibliographic Details
Main Authors: Hörl, Susanne, Banki, Zoltan, Huber, Georg, Ejaz, Asim, Müllauer, Brigitte, Willenbacher, Ella, Steurer, Michael, Stoiber, Heribert
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2013
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856969/
https://ncbi.nlm.nih.gov/pubmed/23850806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.089615
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