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Following DNA chain extension and protein conformational changes in crystals of a Y-family DNA polymerase by Raman crystallography
Y-family DNA polymerases are known to bypass DNA lesions in vitro and in vivo. Sulfolobus solfataricus DNA polymerase (Dpo4) was chosen as a model Y-family enzyme for investigating the mechanism of DNA synthesis in single crystals. Crystals of Dpo4 in complexes with DNA (the binary complex) in the p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855550/ https://ncbi.nlm.nih.gov/pubmed/23855392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400524h |
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