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Mice Overexpressing β-1,4-Galactosyltransferase I Are Resistant to TNF-Induced Inflammation and DSS-Induced Colitis

Glycosylation is an essential post-translational modification, which determines the function of proteins and important processes such as inflammation. β-1,4-galactosyltransferase I (βGalT1) is a key enzyme involved in the addition of galactose moieties to glycoproteins. Intestinal mucins are glycopr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vanhooren, Valerie, Vandenbroucke, Roosmarijn E., Dewaele, Sylviane, Van Hamme, Evelien, Haigh, Jody J., Hochepied, Tino, Libert, Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855152/
https://ncbi.nlm.nih.gov/pubmed/24339869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079883
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