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Targeted Ablation of Crb1 and Crb2 in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis

Development in the central nervous system is highly dependent on the regulation of the switch from progenitor cell proliferation to differentiation, but the molecular and cellular events controlling this process remain poorly understood. Here, we report that ablation of Crb1 and Crb2 genes results i...

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Detalhes bibliográficos
Main Authors: Pellissier, Lucie P., Alves, Celso Henrique, Quinn, Peter M., Vos, Rogier M., Tanimoto, Naoyuki, Lundvig, Ditte M. S., Dudok, Jacobus J., Hooibrink, Berend, Richard, Fabrice, Beck, Susanne C., Huber, Gesine, Sothilingam, Vithiyanjali, Garcia Garrido, Marina, Le Bivic, André, Seeliger, Mathias W., Wijnholds, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854796/
https://ncbi.nlm.nih.gov/pubmed/24339791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003976
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