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Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways
Nonsense-mediated mRNA decay (NMD) is a eukaryotic post-transcriptional gene regulation mechanism that eliminates mRNAs with the termination codon (TC) located in an unfavorable environment for efficient translation termination. The best-studied NMD-targeted mRNAs contain premature termination codon...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854533/ https://ncbi.nlm.nih.gov/pubmed/23962664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.038893.113 |
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