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Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile()

The plant alkaloid ibogaine has promising anti-addictive properties. Albeit not licenced as a therapeutic drug, and despite hints that ibogaine may perturb the heart rhythm, this alkaloid is used to treat drug addicts. We have recently reported that ibogaine inhibits human ERG (hERG) potassium chann...

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Detalhes bibliográficos
Main Authors: Koenig, Xaver, Kovar, Michael, Rubi, Lena, Mike, Agnes K., Lukacs, Peter, Gawali, Vaibhavkumar S., Todt, Hannes, Hilber, Karlheinz, Sandtner, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853361/
https://ncbi.nlm.nih.gov/pubmed/23707769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.05.012
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