Nanomechanical analysis of insulinoma cells after glucose and capsaicin stimulation using atomic force microscopy

AIM: Glucose stimulates insulin secretion from pancreatic islet β cells by altering ion channel activity and membrane potential in the β cells. TRPV1 channel is expressed in the β cells and capsaicin induces insulin secretion similarly to glucose. This study aims to investigate the biophysical prope...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Rui-guo, Xi, Ning, Lai, King Wai-chiu, Zhong, Bei-hua, Fung, Carmen Kar-man, Qu, Chen-geng, Wang, Donna H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852895/
https://ncbi.nlm.nih.gov/pubmed/21623392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.56
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