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Acteoside Suppresses RANKL-Mediated Osteoclastogenesis by Inhibiting c-Fos Induction and NF-κB Pathway and Attenuating ROS Production

Numerous studies have reported that inflammatory cytokines are important mediators for osteoclastogenesis, thereby causing excessive bone resorption and osteoporosis. Acteoside, the main active compound of Rehmannia glutinosa, which is used widely in traditional Oriental medicine, has anti-inflammat...

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Autori principali: Lee, Seung-Youp, Lee, Keun-Soo, Yi, Sea Hyun, Kook, Sung-Ho, Lee, Jeong-Chae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851776/
https://ncbi.nlm.nih.gov/pubmed/24324641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080873
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