Acteoside Suppresses RANKL-Mediated Osteoclastogenesis by Inhibiting c-Fos Induction and NF-κB Pathway and Attenuating ROS Production

Numerous studies have reported that inflammatory cytokines are important mediators for osteoclastogenesis, thereby causing excessive bone resorption and osteoporosis. Acteoside, the main active compound of Rehmannia glutinosa, which is used widely in traditional Oriental medicine, has anti-inflammat...

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Autores principales: Lee, Seung-Youp, Lee, Keun-Soo, Yi, Sea Hyun, Kook, Sung-Ho, Lee, Jeong-Chae
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851776/
https://ncbi.nlm.nih.gov/pubmed/24324641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080873
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