HOXB7 mRNA is overexpressed in pancreatic ductal adenocarcinomas and its knockdown induces cell cycle arrest and apoptosis

BACKGROUND: Human homeobox genes encode nuclear proteins that act as transcription factors involved in the control of differentiation and proliferation. Currently, the role of these genes in development and tumor progression has been extensively studied. Recently, increased expression of HOXB7 homeo...

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Main Authors: Chile, Thais, Fortes, Maria Angela Henriques Zanella, Corrêa-Giannella, Maria Lúcia Cardillo, Brentani, Helena Paula, Maria, Durvanei Augusto, Puga, Renato David, de Paula, Vanessa de Jesus R, Kubrusly, Marcia Saldanha, Novak, Estela Maria, Bacchella, Telésforo, Giorgi, Ricardo Rodrigues
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851693/
https://ncbi.nlm.nih.gov/pubmed/24088503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-451
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