Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat

The metabotropic glutamate receptor 7 (mGluR7) negative allosteric modulator, 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazolo[4,5-c]pyridin-4(5H)-one (MMPIP), was locally microinjected into the ventrolateral periaqueductal gray (VL PAG) and the effect on pain responses in formalin and spare ner...

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Bibliografske podrobnosti
Main Authors: Palazzo, Enza, Marabese, Ida, Luongo, Livio, Boccella, Serena, Bellini, Giulia, Giordano, Maria Elvira, Rossi, Francesca, Scafuro, Mariantonietta, Novellis, Vito de, Maione, Sabatino
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846361/
https://ncbi.nlm.nih.gov/pubmed/24004843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-9-44
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