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Impact of reconstituted cytosol on protein stability

Protein stability is usually studied in simple buffered solutions, but most proteins function inside cells, where the heterogeneous and crowded environment presents a complex, nonideal system. Proteins are expected to behave differently under cellular crowding owing to two types of contacts: hard-co...

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Bibliographic Details
Main Authors: Sarkar, Mohona, Smith, Austin E., Pielak, Gary J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845188/
https://ncbi.nlm.nih.gov/pubmed/24218610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312678110
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