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Antitumor and modeling studies of a penetratin-peptide that targets E2F-1 in small cell lung cancer
E2F-1, a key transcription factor necessary for cell growth, DNA repair, and differentiation, is an attractive target for development of anticancer drugs in tumors that are E2F “oncogene addicted”. We identified a peptide isolated from phage clones that bound tightly to the E2F-1 promoter consensus...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3841214/ https://ncbi.nlm.nih.gov/pubmed/23792570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.25184 |
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