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Nrf2 and NF-κB and Their Concerted Modulation in Cancer Pathogenesis and Progression
Reactive oxygen species, produced by oxidative stress, are implicated in the initiation, promotion, and malignant conversion of carcinogenesis through activation/suppression of redox-sensitive transcription factors. NF-E2-related factor 2 (Nrf2) encodes for antioxidant and general cytoprotection gen...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Molecular Diversity Preservation International
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835087/ https://ncbi.nlm.nih.gov/pubmed/24281078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers2020483 |
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