DNA Methylation Changes during In Vitro Propagation of Human Mesenchymal Stem Cells: Implications for Their Genomic Stability?

Mesenchymal stem cells (MSCs) hold great promise for the treatment of numerous diseases. A major problem for MSC therapeutic use is represented by the very low amount of MSCs which can be isolated from different tissues; thus ex vivo expansion is indispensable. Long-term culture, however, is associa...

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Главные авторы: Bentivegna, Angela, Miloso, Mariarosaria, Riva, Gabriele, Foudah, Dana, Butta, Valentina, Dalprà, Leda, Tredici, Giovanni
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2013
Предметы:
Review Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833027/
https://ncbi.nlm.nih.gov/pubmed/24288545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/192425
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