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Evaluation of p21 promoter for interleukin 12 radiation induced transcriptional targeting in a mouse tumor model

BACKGROUND: Radiation induced transcriptional targeting is a gene therapy approach that takes advantage of the targeting abilities of radiotherapy by using radio inducible promoters to spatially and temporally limit the transgene expression. Cyclin dependent kinase inhibitor 1 (CDKN1A), also known a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kamensek, Urska, Sersa, Gregor, Cemazar, Maja
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832904/
https://ncbi.nlm.nih.gov/pubmed/24219565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-136
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