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DIM (3,3′-diindolylmethane) confers protection against ionizing radiation by a unique mechanism

DIM (3,3′-diindolylmethane), a small molecule compound, is a proposed cancer preventive agent that can be safely administered to humans in repeated doses. We report that administration of DIM in a multidose schedule protected rodents against lethal doses of total body irradiation up to 13 Gy, whethe...

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Main Authors: Fan, Saijun, Meng, Qinghui, Xu, Jiaying, Jiao, Yang, Zhao, Lin, Zhang, Xiaodong, Sarkar, Fazlul H., Brown, Milton L., Dritschilo, Anatoly, Rosen, Eliot M.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831962/
https://ncbi.nlm.nih.gov/pubmed/24127581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308206110
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