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Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: Genetic model for immunodeficiency disease

The inherited deficiency of purine-nucleoside phosphorylase (PNPase; purine-nucleoside:orthophosphate ribosyltransferase, EC 2.4.2.1) in humans is associated with a severe deficiency of the T lymphocytes of the immune system. Because of the unsatisfactory nature of previously described model systems...

詳細記述

保存先:
書誌詳細
主要な著者: Ullman, Buddy, Gudas, Lorraine J., Clift, Shirley M., Martin, David W.
フォーマット: Artigo
言語:Inglês
出版事項: 1979
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC383191/
https://ncbi.nlm.nih.gov/pubmed/108675
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