The proinsulin/insulin (PI/I) ratio is reduced by postprandial targeting therapy in type 2 diabetes mellitus: a small-scale clinical study

BACKGROUND: An elevated PI/I ratio is attributable to increased secretory demand on β-cells. However, the effect of postprandial targeting therapy on proinsulin level is unknown. We evaluated the metabolic effect of glinide and sulfonylurea (SU) using the meal tolerance test (MTT). METHODS: MTT was...

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Autori principali: Ohkura, Tsuyoshi, Inoue, Kazuoki, Fujioka, Youhei, Nakanishi, Risa, Shiochi, Hideki, Sumi, Keisuke, Yamamoto, Naoya, Matsuzawa, Kazuhiko, Izawa, Shoichiro, Ohkura, Hiroko, Kato, Masahiko, Yamamoto, Kazuhiro, Taniguchi, Shin-ichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829708/
https://ncbi.nlm.nih.gov/pubmed/24215809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-453
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