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Toward a Molecular Classification of Colorectal Cancer: The Role of BRAF
Different genetic aberrations of BRAF have been reported in various malignancies. BRAF is member of the RAS/RAF/MEK/ERK pathway and constitutive activity of this pathway can lead to increased cellular growth, invasion, and metastasis. The most common activating BRAF mutation in colorectal cancer is...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828559/ https://ncbi.nlm.nih.gov/pubmed/24298448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00281 |
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