Mitochondrial Transcription Factors TFA, TFB1 and TFB2: A Search for DNA Variants/Haplotypes and the Risk of Cardiac Hypertrophy

Mitochondrial transcription factors mtTFA, mtTFB1 and mtTFB2 are required for the replication of mitochondrial DNA (mtDNA), regulating the number of mtDNA copies. Mice with a mtTFA deletion showed a reduced number of mtDNA copies, a reduction in respiratory chain activity, and a characteristic dilat...

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Main Authors: Alonso-Montes, Cristina, Castro, Mónica G., Reguero, Julián R., Perrot, Andreas, Özcelik, Cemil, Geier, Christian, Posch, Maximilian G., Morís, César, Alvarez, Victoria, Ruiz-Ortega, Marta, Coto, Eliecer
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827797/
https://ncbi.nlm.nih.gov/pubmed/19096125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/575323
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