Silibinin inhibits the production of pro-inflammatory cytokines through inhibition of NF-κB signaling pathway in HMC-1 human mast cells

BACKGROUND: Silibinin is the major active molecule of silymarin, the mixture of flavonolignans extracted from Cirsium japonicum. It has been used for the treatment of hepatitis and inflammation-related diseases. In the present study, the effects of silibinin on allergic inflammation and its signalin...

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Hlavní autoři: Kim, Beom-Rak, Seo, Hye-Sook, Ku, Jin-Mo, Kim, Gyung-Jun, Jeon, Chan Yong, Park, Jong Hyeong, Jang, Bo-Hyoung, Park, Sun-Ju, Shin, Yong-Cheol, Ko, Seong-Gyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Basel 2013
Témata:
Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825293/
https://ncbi.nlm.nih.gov/pubmed/24045679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-013-0640-1
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