Efficacy of thalidomide for the treatment of amyotrophic lateral sclerosis: A phase II open label clinical trial

Neuroinflammation through the cytokine, tumor necrosis factor-alpha (TNF-α) is thought to play an important role in the pathogenesis of amyotrophic lateral sclerosis (ALS). We conducted a preliminary phase II trial of thalidomide, which reduces levels of TNF-α pre-transcriptionally and post-transcri...

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Main Authors: STOMMEL, ELIJAH W., COHEN, JEFFREY A., FADUL, CAMILO E., COGBILL, CHRISTOPHER H., GRABER, DAVID J., KINGMAN, LINDA, MACKENZIE, TODD, SMITH, JACQUELINE Y. CHANNON, HARRIS, BRENT T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820489/
https://ncbi.nlm.nih.gov/pubmed/19922130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/17482960802709416
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