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A unifying framework for robust association testing, estimation, and genetic model selection using the generalized linear model

The analysis of genome-wide genetic association studies generally starts with univariate statistical tests of each single-nucleotide polymorphism. The standard approach is the Cochran-Armitage trend test or its logistic regression equivalent although this approach can lose considerable power if the...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Loley, Christina, König, Inke R, Hothorn, Ludwig, Ziegler, Andreas
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820468/
https://ncbi.nlm.nih.gov/pubmed/23572026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.62
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