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A unifying framework for robust association testing, estimation, and genetic model selection using the generalized linear model
The analysis of genome-wide genetic association studies generally starts with univariate statistical tests of each single-nucleotide polymorphism. The standard approach is the Cochran-Armitage trend test or its logistic regression equivalent although this approach can lose considerable power if the...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820468/ https://ncbi.nlm.nih.gov/pubmed/23572026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.62 |
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