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Thrombospondin 1 activates the macrophage Toll-like receptor 4 pathway

Previously, we demonstrated that macrophages from thrombospondin 1 (TSP1)-deficient mice have a reduced inflammatory phenotype, suggesting that TSP1 plays a role in macrophage activation. In this study, we determined how TSP1 regulates macrophage function. We found that recombinant or purified plate...

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Detalhes bibliográficos
Main Authors: Li, Yanzhang, Qi, Xinyu, Tong, Xiaopeng, Wang, Shuxia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818315/
https://ncbi.nlm.nih.gov/pubmed/23954950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2013.32
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