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Gremlin-1 Is an Inhibitor of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerotic Plaque Growth in ApoE(−/−) Mice

Monocyte infiltration and macrophage formation are pivotal steps in atherosclerosis and plaque vulnerability. Gremlin-1/Drm is crucial in embryo-/organogenesis and has been shown to be expressed in the adult organism at sites of arterial injury and to inhibit monocyte migration. The purpose of the p...

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Autori principali: Müller, Iris, Schönberger, Tanja, Schneider, Martina, Borst, Oliver, Ziegler, Melanie, Seizer, Peter, Leder, Christoph, Müller, Karin, Lang, Michael, Appenzeller, Florian, Lunov, Oleg, Büchele, Berthold, Fahrleitner, Manuela, Olbrich, Marcus, Langer, Harald, Geisler, Tobias, Lang, Florian, Chatterjee, Madhumita, de Boer, Jan Freark, Tietge, Uwe J. F., Bernhagen, Jürgen, Simmet, Thomas, Gawaz, Meinrad
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814759/
https://ncbi.nlm.nih.gov/pubmed/24003215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477745
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