Nuclear Fragile X Mental Retardation Protein Is localized to Cajal Bodies

Fragile X syndrome is caused by loss of function of a single gene encoding the Fragile X Mental Retardation Protein (FMRP). This RNA-binding protein, widely expressed in mammalian tissues, is particularly abundant in neurons and is a component of messenger ribonucleoprotein (mRNP) complexes present...

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Hlavní autoři: Dury, Alain Y., El Fatimy, Rachid, Tremblay, Sandra, Rose, Timothy M., Côté, Jocelyn, De Koninck, Paul, Khandjian, Edouard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814324/
https://ncbi.nlm.nih.gov/pubmed/24204304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003890
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